Steward Centers for Cancer CareCancer CareOur Cancer CentersSt. Elizabeth's Medical Center

NanoKnife® IRE System

NanoKnife St. Elizabeth’s Medical Center for Cancer Care provides access to the latest therapies and technologies for all patients diagnosed with cancer. Our departments of radiology, oncology and surgery offer the NanoKnife® IRE System, which is a cutting-edge technology, approved by the FDA, for soft tissue ablation. This technology offers a new treatment option for patients with cancers of the liver, biliary system, kidneys, prostate, lungs and pancreas.

The NanoKnife® IRE System is a minimally invasive tissue ablation system that uses an electrical current to destroy targeted soft tissue in tumors of the liver, kidney, lung and pancreas, leaving the normal surrounding tissues viable and untouched. The process, called irreversible electroporation, causes cell death of targeted tissue by damaging the cell membrane and causing cellular contents to leak. The technology offers precise control that allows treatment of lesions near sensitive structures like nerves and blood vessels that cannot be treated by other means. 

Features of the NanoKnife® IRE System include:

  • Physicians can perform ablative surgery that may not be treatable with surgery or radiation 
  • Patients undergo general anesthesia and experience little pain after the procedure 
  • Treatment requires only a brief hospital stay and some patients go home the same day 
  • With few side effects or scarring, the procedure can be repeated if new lesions develop elsewhere in the body 

Our specialists who use the NanoKnife® IRE System are:


St. Elizabeth's Medical Center Radiation Oncology Center
Radiation Oncology, Connell Pavilion, 2nd Floor
Phone: 617-789-3232

Dana-Farber Cancer Institute at St. Elizabeth's Medical Center
Outpatient Center, Cushing Pavilion, 5th Floor
Phone: 617-789-2903

St. Elizabeth’s Center for Breast Care
St. Margaret's Center, 5
Phone: 617-789-2400

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